The discovery of insulin is one of the biggest breakthroughs in medicine - and one of the most debated Nobel Prizes.
It is January, 1922, Toronto, Canada. 14-year-old Leonard Thompson is the first person with diabetes to receive insulin. The test is a success: Leonard, who before the insulin shots was near death, rapidly regains his strength and appetite.
The news of the successful test treatment rapidly spread, and in 1923, Frederick Banting and John Macleod share the Nobel Prize in Physiology or Medicine for the discovery of insulin.
However, Banting was furious with the choice of recipients. He felt that that the prize should have been shared between him and his assistant – medical student Charles Best – not between him and the senior diabetes researcher Macleod.
To credit Best, Banting shared his cash award with him. Macleod, in turn, shared his cash award with biochemist Bertram Collip who had joined the team during the testing phase.
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